ZNF562

Across TCGA cell cohorts, ZNF562 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF562-associated genes across cancer lineages are TAFA1, OR2V1, and LBHD2. Each is linked with ZNF562 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF562-to-partner and partner-to-ZNF562 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by ZNF562-low versus ZNF562-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF562→partner) and Y-score (partner→ZNF562) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAFA1 →	+0.402	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
LARGE_INTESTINE	LBHD2 →	+0.125	+4.273	<.001	.006	3	1
BLOOD_Leukemia	SLC22A8 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	MYMK →	+0.024	+4.922	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TAFA1 by ZNF562 expression — LARGE_INTESTINE

Explore this box plot interactively →