Across TCGA patient cohorts, ZNF560 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF560-associated genes across cancer lineages are Notch1, Caspase-7-cleavedD198, and MSH6. Each is linked with ZNF560 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF560-to-partner and partner-to-ZNF560 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF560→partner) and Y-score (partner→ZNF560) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.109	+1.290	.010	.034	3	3
UCEC	Caspase-7-cleavedD198 →	+0.704	+2.682	<.001	<.001	3	3
LUAD	MSH6 →	+0.463	+2.824	.004	.034	3	2
LUAD	PCNA →	+0.229	+2.820	.014	.035	3	2
UCEC	ERK2 →	+0.151	+1.415	.009	.040	3	2
UCEC	Heregulin →	-0.084	-1.571	.024	.032	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZNF560 survival (RNA) · tumor vs normal (RNA) · all ZNF560 data types