ZNF559

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF559 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF559-associated genes across cancer lineages are C-Raf, 14-3-3_beta, and ERK2. Each is linked with ZNF559 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF559-to-partner and partner-to-ZNF559 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF559→partner) and Y-score (partner→ZNF559) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADC-Raf →+0.244+3.034<.001.01733
UCEC14-3-3_beta →-0.082-2.673.012.00532
UCECERK2 →+0.179+2.000.004<.00132
UCECFoxM1 →+0.195+1.594.020.02132
UCECJNK_pT183_Y185 →-0.178-2.662.001<.00132
COADMEK1 →+0.235+2.195.012.03432
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

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