Across TCGA cell cohorts, ZNF559 mutation is significantly associated with the RNA expression of many other genes, with 213 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF559-associated genes across cancer lineages are JOSD1, VAPA, and TMEM147. Each is linked with ZNF559 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF559-to-partner and partner-to-ZNF559 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF559→partner) and Y-score (partner→ZNF559) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	JOSD1 →	+0.532	+3.212	.009	.006	3	1
LARGE_INTESTINE	VAPA →	+0.666	+3.212	<.001	.006	3	1
LARGE_INTESTINE	TMEM147 →	+0.477	+3.212	.001	.006	3	1
LARGE_INTESTINE	CLCN3 →	+0.707	+3.212	.004	.006	3	1
LARGE_INTESTINE	C12orf57 →	+0.785	+3.212	.008	.006	3	1
LARGE_INTESTINE	RIC8B →	+0.587	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 213 associations by consensus.

Exploration

ZNF559 survival (RNA) · tumor vs normal (RNA) · all ZNF559 data types