ZNF557

Across TCGA patient cohorts, ZNF557 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,520 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF557-associated proteins across cancer lineages are KHSRP, RANBP3, and SAFB. Each is linked with ZNF557 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF557-to-partner and partner-to-ZNF557 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF557 versus KHSRP in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF557→partner) and Y-score (partner→ZNF557) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KHSRP →	+0.315	+0.390	<.001	<.001	3	9
BRCA	RANBP3 →	+0.243	+0.399	<.001	<.001	3	6
GBM	SAFB →	+0.352	+0.350	<.001	<.001	3	6
GBM	SAFB2 →	+0.288	+0.243	<.001	<.001	3	6
GBM	HDGFL2 →	+0.367	+0.318	<.001	<.001	3	6
GBM	P4HB →	-0.338	-0.275	.004	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,520 associations by consensus.

ZNF557 vs KHSRP — GBM

Explore this scatter interactively →