ZNF557

Across TCGA cell cohorts, ZNF557 protein abundance is significantly associated with the go_rna of many other GO terms, with 694 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible ZNF557-associated GO terms across cancer lineages are Zinc ion transmembrane transport, Positive regulation of striated muscle cell differentiation, and Translational readthrough. Each is linked with ZNF557 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF557-to-partner and partner-to-ZNF557 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion transmembrane transport grouped by ZNF557-low versus ZNF557-high in LUNG_NSCLC_LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF557→partner) and Y-score (partner→ZNF557) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Zinc ion transmembrane transport →	-0.068	-0.994	.007	.004	3	4
BREAST	Positive regulation of striated muscle cell differentiation →	-0.157	-1.970	.002	.003	3	3
OVARY	Translational readthrough →	+0.087	+0.824	.005	.009	3	3
LUNG_SCLC	Nucleoside metabolic process →	+0.201	+2.207	<.001	<.001	2	4
CNS	Regulation of neuron apoptotic process →	+0.050	+1.575	.002	.002	3	3
OVARY	Selenocysteine incorporation →	+0.087	+0.824	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 694 associations by consensus.

Zinc ion transmembrane transport by ZNF557 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →