ZNF554

Across TCGA patient cohorts, ZNF554 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,783 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF554-associated proteins across cancer lineages are LMNB2, VEZF1, and CASP4. Each is linked with ZNF554 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF554-to-partner and partner-to-ZNF554 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF554 versus LMNB2 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF554→partner) and Y-score (partner→ZNF554) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LMNB2 →	+0.512	+0.518	<.001	<.001	3	8
HNSC	VEZF1 →	+0.464	+0.790	<.001	<.001	3	6
GBM	CASP4 →	-0.640	-0.447	<.001	<.001	3	6
GBM	EPM2AIP1 →	+0.320	+0.387	<.001	.001	3	6
GBM	EPS15_S221 →	-0.428	-0.424	.001	<.001	3	6
GBM	NCF2 →	-0.539	-0.384	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,783 associations by consensus.

ZNF554 vs LMNB2 — GBM

Explore this scatter interactively →