ZNF554

Across TCGA patient cohorts, ZNF554 mutation is significantly associated with the RNA expression of many other genes, with 978 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF554-associated genes across cancer lineages are MIR8082, RAB11AP1, and RPSAP32. Each is linked with ZNF554 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF554-to-partner and partner-to-ZNF554 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8082 grouped by ZNF554-low versus ZNF554-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF554→partner) and Y-score (partner→ZNF554) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8082 →	+0.291	+2.059	<.001	.005	3	2
COAD	RAB11AP1 →	+0.243	+3.588	<.001	.007	3	2
COAD	RPSAP32 →	+0.143	+3.843	<.001	.004	3	2
UCEC	BAG3 →	+0.649	+2.386	<.001	.002	3	2
UCEC	KCTD9 →	+0.498	+1.858	.006	.005	3	2
UCEC	SETDB2 →	+0.394	+1.947	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 978 associations by consensus.

MIR8082 by ZNF554 expression — UCEC

Explore this box plot interactively →