ZNF554

Across TCGA cell cohorts, ZNF554 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF554-associated genes across cancer lineages are OR52L1, CABP5, and FCN2. Each is linked with ZNF554 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF554-to-partner and partner-to-ZNF554 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52L1 grouped by ZNF554-low versus ZNF554-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF554→partner) and Y-score (partner→ZNF554) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR52L1 →	+0.070	+4.606	<.001	.001	3	2
BLOOD_Lymphoma	CABP5 →	+0.011	+4.452	<.001	.001	3	1
BLOOD_Lymphoma	FCN2 →	+0.036	+5.129	<.001	<.001	3	1
BLOOD_Lymphoma	LMX1A →	+0.031	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	SLC38A8 →	+0.090	+4.606	<.001	.001	3	1
BLOOD_Lymphoma	PGK2 →	+0.020	+3.523	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

OR52L1 by ZNF554 expression — BLOOD_Lymphoma

Explore this box plot interactively →