ZNF552

Across TCGA patient cohorts, ZNF552 mutation is significantly associated with the RNA expression of many other genes, with 2,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF552-associated genes across cancer lineages are VN1R32P, RNU6-871P, and RNU6-1220P. Each is linked with ZNF552 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF552-to-partner and partner-to-ZNF552 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R32P grouped by ZNF552-low versus ZNF552-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF552→partner) and Y-score (partner→ZNF552) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VN1R32P →	+0.069	+5.444	<.001	.002	3	2
CESC	RNU6-871P →	+0.245	+4.812	<.001	.006	3	2
CESC	RNU6-1220P →	+0.246	+5.837	<.001	.001	3	2
CESC	RNU6-1261P →	+0.253	+6.584	<.001	<.001	3	2
BRCA	RPS29P26 →	+0.173	+8.055	<.001	.007	3	2
STAD	LCEP1 →	+0.236	+5.463	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,209 associations by consensus.

VN1R32P by ZNF552 expression — BLCA

Explore this box plot interactively →