Across TCGA patient cohorts, ZNF551 protein abundance is significantly associated with the RNA expression of many other genes, with 473 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF551-associated genes across cancer lineages are XBP1, UBL4A, and KATNAL1. Each is linked with ZNF551 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF551-to-partner and partner-to-ZNF551 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF551→partner) and Y-score (partner→ZNF551) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XBP1 →	+0.854	+1.594	.009	.002	3	1
LSCC	UBL4A →	-0.530	-1.330	.003	.003	3	1
LSCC	KATNAL1 →	-0.524	-1.109	<.001	.003	3	1
LSCC	ZFAND1 →	-0.639	-1.177	.003	.003	3	1
LSCC	TBCB →	-0.766	-1.416	.004	.003	3	1
LSCC	POLR2I →	-0.846	-1.638	.008	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 473 associations by consensus.

Exploration

ZNF551 survival (RNA) · tumor vs normal (RNA) · all ZNF551 data types