Across TCGA patient cohorts, ZNF551 mutation is significantly associated with the RNA expression of many other genes, with 3,504 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF551-associated genes across cancer lineages are RNU6-178P, CDY3P, and SULT6B1. Each is linked with ZNF551 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF551-to-partner and partner-to-ZNF551 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF551→partner) and Y-score (partner→ZNF551) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-178P →	+0.478	+2.759	<.001	.006	3	3
HNSC	CDY3P →	+0.022	+4.468	<.001	.006	3	3
HNSC	SULT6B1 →	+0.075	+4.161	.005	.002	3	2
HNSC	OR5P3 →	+0.072	+3.301	.001	.008	3	2
HNSC	OR51M1 →	+0.056	+3.770	<.001	.005	3	2
HNSC	RNU6-707P →	+0.225	+4.339	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,504 associations by consensus.

Exploration

ZNF551 survival (RNA) · tumor vs normal (RNA) · all ZNF551 data types