Across TCGA patient cohorts, ZNF551 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF551-associated genes across cancer lineages are PKC-b-II_pS660, Shc_pY317, and Bax. Each is linked with ZNF551 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF551-to-partner and partner-to-ZNF551 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF551→partner) and Y-score (partner→ZNF551) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-b-II_pS660 →	-0.171	-1.064	.043	.048	3	3
UCEC	Shc_pY317 →	-0.113	-1.064	.014	.048	3	3
UCEC	Bax →	+0.161	+1.064	.028	.048	3	3
COAD	Cyclin-E2 →	+0.253	+2.832	.047	.034	2	4
UCEC	EGFR_pY1068 →	-0.216	-1.700	.005	.001	3	2
UCEC	eIF4E →	+0.161	+2.235	.012	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

ZNF551 survival (RNA) · tumor vs normal (RNA) · all ZNF551 data types