Across TCGA cell cohorts, ZNF551 mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF551-associated genes across cancer lineages are UNC1215, Luminespib, and 123829. Each is linked with ZNF551 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF551-to-partner and partner-to-ZNF551 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF551→partner) and Y-score (partner→ZNF551) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UNC1215 →	+0.253	+2.716	.012	.042	3	1
LARGE_INTESTINE	Luminespib →	+0.738	+2.646	.014	.047	3	1
LARGE_INTESTINE	123829 →	+0.622	+2.649	.032	.046	2	1
LARGE_INTESTINE	GSK2830371A →	+0.325	+2.649	.047	.046	1	1
LARGE_INTESTINE	Sabutoclax →	+0.560	+2.769	.007	.040	1	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.534	+2.646	.032	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ZNF551 survival (RNA) · tumor vs normal (RNA) · all ZNF551 data types