ZNF549

Across TCGA cell cohorts, ZNF549 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,178 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF549-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Transcription initiation at RNA polymerase II promoter, and Nucleic acid catabolic process. Each is linked with ZNF549 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF549-to-partner and partner-to-ZNF549 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ZNF549-low versus ZNF549-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF549→partner) and Y-score (partner→ZNF549) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.093	+0.622	<.001	<.001	3	11
BLOOD_Lymphoma	Transcription initiation at RNA polymerase II promoter →	+0.057	+1.586	<.001	<.001	3	10
BONE	Nucleic acid catabolic process →	+0.060	+0.592	.001	<.001	3	10
BONE	Regulation of DNA-templated transcription initiation →	+0.064	+0.682	.002	<.001	3	10
BONE	Positive regulation of cytoplasmic translation →	+0.089	+0.559	.001	.002	3	10
SOFT_TISSUE	Stress granule assembly →	+0.086	+0.502	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,178 associations by consensus.

Epigenetic regulation of gene expression by ZNF549 expression — BONE

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