Across TCGA patient cohorts, ZNF548 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,503 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF548-associated proteins across cancer lineages are EPM2AIP1, KIF1B_S1487, and VEZF1. Each is linked with ZNF548 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF548-to-partner and partner-to-ZNF548 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF548→partner) and Y-score (partner→ZNF548) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EPM2AIP1 →	+0.379	+0.510	<.001	<.001	3	5
LSCC	KIF1B_S1487 →	-0.412	-0.393	.001	.001	3	5
HNSC	VEZF1 →	+0.385	+0.452	<.001	<.001	3	5
OV	MMP2 →	+0.629	+0.683	.006	.001	3	5
BRCA	ARHGAP35 →	+0.356	+0.518	<.001	<.001	3	5
CCRCC	TLN2 →	+0.461	+0.285	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,503 associations by consensus.

Exploration

ZNF548 survival (RNA) · tumor vs normal (RNA) · all ZNF548 data types