Across TCGA cell cohorts, ZNF548 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF548-associated genes across cancer lineages are MAGEB4, STRA8, and ZNF804B. Each is linked with ZNF548 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF548-to-partner and partner-to-ZNF548 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF548→partner) and Y-score (partner→ZNF548) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.022	+4.415	<.001	.007	3	1
LARGE_INTESTINE	STRA8 →	+0.161	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	DAZ2 →	+0.252	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZNF548 survival (RNA) · tumor vs normal (RNA) · all ZNF548 data types