Across TCGA patient cohorts, ZNF546 protein abundance is significantly associated with the RNA expression of many other genes, with 242 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF546-associated genes across cancer lineages are ABHD4, FNDC3A, and GSDME. Each is linked with ZNF546 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF546-to-partner and partner-to-ZNF546 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF546→partner) and Y-score (partner→ZNF546) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABHD4 →	+0.666	+0.289	.009	.001	3	1
UCEC	FNDC3A →	+0.606	+0.290	.005	.001	3	1
UCEC	GSDME →	+1.853	+0.290	.003	.001	3	1
UCEC	HOXA1 →	+1.026	+0.290	.007	.001	3	1
UCEC	RLN1 →	-0.736	-0.290	.001	.001	3	1
UCEC	PPP1R9B →	+1.006	+0.289	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 242 associations by consensus.

Exploration

ZNF546 survival (RNA) · tumor vs normal (RNA) · all ZNF546 data types