Across TCGA cell cohorts, ZNF546 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF546-associated GO terms across cancer lineages are DNA biosynthetic process, Regulation of telomere capping, and Intraciliary anterograde transport. Each is linked with ZNF546 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF546-to-partner and partner-to-ZNF546 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF546→partner) and Y-score (partner→ZNF546) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA biosynthetic process →	+0.088	+0.897	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere capping →	+0.125	+0.360	<.001	.002	3	14
OVARY	Intraciliary anterograde transport →	+0.116	+0.842	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of telomere maintenance →	+0.078	+0.286	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.064	+0.401	.002	<.001	3	12
URINARY_TRACT	Regulation of telomere maintenance via telomerase →	+0.083	+0.869	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Exploration

ZNF546 survival (RNA) · tumor vs normal (RNA) · all ZNF546 data types