Across TCGA cell cohorts, ZNF544 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF544-associated genes across cancer lineages are DEFA3, TEX55, and HSFY2. Each is linked with ZNF544 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF544-to-partner and partner-to-ZNF544 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF544→partner) and Y-score (partner→ZNF544) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DEFA3 →	+0.090	+5.169	<.001	.004	3	1
CNS	TEX55 →	+0.029	+4.321	<.001	<.001	3	1
CNS	HSFY2 →	+0.044	+4.643	<.001	<.001	3	1
CNS	C1orf146 →	+0.022	+3.459	<.001	.006	3	1
BLOOD_Leukemia	BRDT →	+0.147	+3.342	<.001	.006	3	1
BLOOD_Leukemia	GUCA1C →	+0.030	+4.969	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

ZNF544 survival (RNA) · tumor vs normal (RNA) · all ZNF544 data types