ZNF543

Across TCGA patient cohorts, ZNF543 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,733 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF543-associated proteins across cancer lineages are TRIM28, ZNF460, and IRF2BP1. Each is linked with ZNF543 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF543-to-partner and partner-to-ZNF543 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF543 versus TRIM28 in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF543→partner) and Y-score (partner→ZNF543) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.484	+0.525	<.001	<.001	3	7
LSCC	ZNF460 →	+0.496	+0.464	<.001	<.001	3	6
GBM	IRF2BP1 →	+0.383	+0.467	<.001	<.001	3	6
GBM	SAE1 →	+0.394	+0.458	<.001	<.001	3	5
LSCC	SEC23IP →	-0.189	-0.338	.002	.008	3	5
LSCC	SF3B3 →	+0.235	+0.550	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,733 associations by consensus.

ZNF543 vs TRIM28 — GBM

Explore this scatter interactively →