ZNF542P

Across TCGA pan-cancer cohorts, ZNF542P RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ZNF542P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF542P RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF542P is over-expressed in tumor, although a few such as KIRC and HNSC show the opposite, repressed pattern.

KIRC, HNSC, and COAD are the cancer types where ZNF542P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF542P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	−1.105	<.001	12	view →
HNSC	Male	All	−0.759	<.001	12	view →
COAD	Male	All	−0.832	<.001	9	view →
THCA	All	All	−0.248	.004	9	view →
KICH	Male	II,III,IV	−1.471	<.001	7	view →
KIRP	All	All	−1.187	<.001	7	view →
LUSC	Male	II,III,IV	−0.862	<.001	7	view →
UCEC	All	All	−0.869	<.001	4	view →
LUAD	All	All	−0.337	.003	4	view →
STAD	All	All	−0.676	.004	3	view →
READ	Female	All	−1.652	.002	2	view →
PAAD	All	All	−0.752	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ZNF542P–KIRC

Open the KIRC breakdown →