ZNF541

Across TCGA pan-cancer cohorts, ZNF541 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF541 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher ZNF541 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF541 expression acts as an unfavorable survival marker.

MESO, TGCT, and OV are the cancer types where ZNF541 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
TGCT	DFS	Median	All	0.174	0.801	.041	6	view →
OV	DFS	Median	All	0.132	0.541	.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZNF541–MESO (DFS)

Open the MESO breakdown →