ZNF541

Across TCGA patient cohorts, ZNF541 protein abundance is significantly associated with the RNA expression of many other genes, with 749 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF541-associated genes across cancer lineages are PRCD, TRBJ2-2, and CCDC197. Each is linked with ZNF541 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF541-to-partner and partner-to-ZNF541 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF541 versus PRCD in GBM, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF541→partner) and Y-score (partner→ZNF541) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRCD →	+0.578	+0.970	.002	.004	3	2
LSCC	TRBJ2-2 →	+1.245	+0.580	.007	.005	3	2
COAD	CCDC197 →	-0.076	-0.356	.003	.009	3	1
COAD	RPL7AP60 →	+0.556	+0.356	.005	.009	3	1
OV	NDFIP2 →	-0.623	-0.963	.009	.003	3	1
OV	UGGT2 →	-0.552	-1.015	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 749 associations by consensus.

ZNF541 vs PRCD — GBM

Explore this scatter interactively →