ZNF541

Across TCGA cell cohorts, ZNF541 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,318 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF541-associated GO terms across cancer lineages are Lysosomal membrane organization, Regulation of macroautophagy, and Negative regulation of myoblast fusion. Each is linked with ZNF541 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF541-to-partner and partner-to-ZNF541 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal membrane organization grouped by ZNF541-low versus ZNF541-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF541→partner) and Y-score (partner→ZNF541) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Lysosomal membrane organization →	+0.097	+0.251	<.001	<.001	3	5
CNS	Regulation of macroautophagy →	+0.035	+0.074	.003	<.001	3	5
OVARY	Negative regulation of myoblast fusion →	+0.069	+0.265	.005	.008	3	5
BLOOD_Leukemia	Cytoplasmic translation →	+0.044	+0.194	.001	.005	3	5
OVARY	Protein transmembrane transport →	+0.032	+0.269	.006	.008	3	5
OVARY	Regulation of stem cell population maintenance →	+0.049	+0.253	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,318 associations by consensus.

Lysosomal membrane organization by ZNF541 expression — OVARY

Explore this box plot interactively →