ZNF540

Across TCGA patient cohorts, ZNF540 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,155 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZNF540-associated proteins across cancer lineages are EIF4G1, PURA, and AGO1. Each is linked with ZNF540 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF540-to-partner and partner-to-ZNF540 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF540 versus EIF4G1 in LSCC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF540→partner) and Y-score (partner→ZNF540) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EIF4G1 →	-0.267	-0.438	.005	<.001	3	10
BRCA	PURA →	+0.391	+0.644	<.001	<.001	3	9
LUAD	AGO1 →	+0.287	+0.604	<.001	<.001	3	9
OV	YME1L1 →	-0.296	-0.751	<.001	.001	3	8
LUAD	RPL5 →	-0.224	-0.678	<.001	<.001	3	8
OV	SORBS3 →	+0.509	+0.738	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,155 associations by consensus.

ZNF540 vs EIF4G1 — LSCC

Explore this scatter interactively →