ZNF540

Across TCGA patient cohorts, ZNF540 mutation is significantly associated with the RNA expression of many other genes, with 3,587 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF540-associated genes across cancer lineages are TSPY14P, KIFBP, and RNU6-904P. Each is linked with ZNF540 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF540-to-partner and partner-to-ZNF540 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY14P grouped by ZNF540-low versus ZNF540-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF540→partner) and Y-score (partner→ZNF540) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	TSPY14P →	+0.042	+2.951	.002	.004	3	3
UCEC	KIFBP →	+0.352	+1.617	.006	<.001	3	3
BLCA	RNU6-904P →	+0.347	+4.859	<.001	.004	3	3
STAD	MIR4769 →	+0.303	+3.396	.002	.009	3	3
UCEC	API5 →	+0.375	+1.595	.006	<.001	3	3
READ	RNVU1-33 →	+0.646	+5.054	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,587 associations by consensus.

TSPY14P by ZNF540 expression — ESCA

Explore this box plot interactively →