ZNF540

Across TCGA cell cohorts, ZNF540 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,942 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF540-associated GO terms across cancer lineages are Spliceosomal complex assembly, Vesicle tethering, and Aggrephagy. Each is linked with ZNF540 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF540-to-partner and partner-to-ZNF540 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by ZNF540-low versus ZNF540-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF540→partner) and Y-score (partner→ZNF540) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Spliceosomal complex assembly →	+0.073	+0.293	.009	.005	2	8
BREAST	Vesicle tethering →	+0.083	+0.507	<.001	.003	3	7
PANCREAS	Aggrephagy →	+0.065	+0.303	.003	.007	3	7
SOFT_TISSUE	Golgi vesicle transport →	+0.038	+0.525	.004	<.001	3	6
SKIN	Early endosome to late endosome transport →	+0.042	+0.309	.006	.002	3	6
BLOOD_Lymphoma	Heterochromatin organization →	+0.041	+0.505	.003	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,942 associations by consensus.

Spliceosomal complex assembly by ZNF540 expression — URINARY_TRACT

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