Across TCGA patient cohorts, ZNF536 protein abundance is significantly associated with the RNA expression of many other genes, with 1,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF536-associated genes across cancer lineages are CSMD2, SLC39A8, and SHISAL2B. Each is linked with ZNF536 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF536-to-partner and partner-to-ZNF536 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF536→partner) and Y-score (partner→ZNF536) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CSMD2 →	+0.956	+3.191	<.001	.001	3	2
GBM	SLC39A8 →	-1.687	-1.252	.001	.003	3	2
GBM	SHISAL2B →	+1.006	+1.581	.003	.008	3	2
GBM	SCLT1 →	+0.616	+1.569	.007	.007	3	2
LSCC	KRT16 →	-3.192	-1.709	.003	.002	3	2
LSCC	CCNI2 →	+0.867	+2.177	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,878 associations by consensus.

Exploration

ZNF536 survival (RNA) · tumor vs normal (RNA) · all ZNF536 data types