Across TCGA patient cohorts, ZNF536 mutation is significantly associated with the total protein of many other genes, with 96 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZNF536-associated genes across cancer lineages are PCNA, ASNS, and Caspase-7-cleavedD198. Each is linked with ZNF536 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF536-to-partner and partner-to-ZNF536 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF536→partner) and Y-score (partner→ZNF536) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PCNA →	+0.202	+3.906	.023	<.001	2	7
STAD	ASNS →	+0.455	+2.137	<.001	<.001	3	5
COAD	Caspase-7-cleavedD198 →	+0.719	+0.951	<.001	.040	3	5
LUSC	HER2 →	+0.187	+1.059	.045	.014	3	4
LUAD	EGFR_pY1068 →	-0.285	-1.662	.011	.008	3	4
STAD	FoxM1 →	+0.354	+1.796	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

Exploration

ZNF536 survival (RNA) · tumor vs normal (RNA) · all ZNF536 data types