Across TCGA cell cohorts, ZNF536 mutation is significantly associated with the RNA expression of many other genes, with 1,541 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF536-associated genes across cancer lineages are RBMXL1, LGALS13, and OR56A4. Each is linked with ZNF536 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF536-to-partner and partner-to-ZNF536 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF536→partner) and Y-score (partner→ZNF536) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RBMXL1 →	+0.498	+2.000	.001	<.001	3	3
PANCREAS	LGALS13 →	+0.060	+5.614	<.001	.002	3	2
LUNG_SCLC	OR56A4 →	+0.063	+1.987	<.001	.006	3	2
LUNG_NSCLC_LUSC	SFT2D3 →	+0.931	+3.514	.008	.008	3	2
LUNG_NSCLC_LUAD	LHX6 →	+1.158	+2.115	<.001	.005	3	2
LARGE_INTESTINE	APPL1 →	+0.544	+2.043	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,541 associations by consensus.

Exploration

ZNF536 survival (RNA) · tumor vs normal (RNA) · all ZNF536 data types