ZNF532

Across TCGA pan-cancer cohorts, ZNF532 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF532 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF532 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF532 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

LUAD, HNSC, and LSCC are the cancer types where ZNF532 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.675	0.818	.032	6	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.883	.015	5	view →
LSCC	OS	Tertile	All	0.926	0.759	.013	4	view →
GBM	OS	Median	All	0.475	0.303	.048	1	view →
CCRCC	DFS	Median	II,III,IV	0.777	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF532–LUAD (DFS)

Open the LUAD breakdown →