ZNF532

Across TCGA patient cohorts, ZNF532 mutation is significantly associated with the RNA expression of many other genes, with 4,205 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF532-associated genes across cancer lineages are HACD3, UBE2G1, and RPL17P50. Each is linked with ZNF532 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF532-to-partner and partner-to-ZNF532 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HACD3 grouped by ZNF532-low versus ZNF532-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF532→partner) and Y-score (partner→ZNF532) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HACD3 →	+0.548	+1.617	<.001	<.001	3	4
UCEC	UBE2G1 →	+0.403	+1.643	<.001	.002	3	4
UCEC	RPL17P50 →	+0.308	+2.758	.002	<.001	3	4
GBM	MIR8053 →	+0.532	+6.209	<.001	<.001	3	3
CESC	RPS6KA1 →	+0.516	+3.331	.005	.005	3	3
COAD	GSR →	+0.527	+2.807	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,205 associations by consensus.

HACD3 by ZNF532 expression — UCEC

Explore this box plot interactively →