Across TCGA patient cohorts, ZNF530 mutation is significantly associated with the RNA expression of many other genes, with 1,342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF530-associated genes across cancer lineages are TUBGCP5, UHRF1, and SLC25A4. Each is linked with ZNF530 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF530-to-partner and partner-to-ZNF530 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF530→partner) and Y-score (partner→ZNF530) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBGCP5 →	+0.458	+2.119	.001	.003	3	2
UCEC	UHRF1 →	+0.971	+2.595	<.001	<.001	3	2
UCEC	SLC25A4 →	+0.485	+2.098	.004	.003	3	2
UCEC	SAR1B →	+0.383	+3.111	.007	<.001	3	2
UCEC	ZDHHC7 →	+0.492	+3.608	<.001	.001	3	2
UCEC	BUB3 →	+0.407	+2.660	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,342 associations by consensus.

Exploration

ZNF530 survival (RNA) · tumor vs normal (RNA) · all ZNF530 data types