Across TCGA patient cohorts, ZNF530 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF530-associated genes across cancer lineages are ATM, C-Raf, and 4E-BP1. Each is linked with ZNF530 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF530-to-partner and partner-to-ZNF530 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF530→partner) and Y-score (partner→ZNF530) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.415	-2.000	.019	.010	3	3
UCEC	C-Raf →	+0.208	+2.000	<.001	.030	3	3
UCEC	4E-BP1 →	+0.355	+3.169	<.001	.018	3	2
UCEC	14-3-3_beta →	-0.108	-3.295	.006	.009	3	1
UCEC	EGFR_pY1068 →	-0.233	-2.000	.018	.010	3	1
UCEC	EGFR →	-0.151	-1.584	.016	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ZNF530 survival (RNA) · tumor vs normal (RNA) · all ZNF530 data types