Across TCGA patient cohorts, ZNF529 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF529-associated genes across cancer lineages are PKC-b-II_pS660, ATM, and Bax. Each is linked with ZNF529 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF529-to-partner and partner-to-ZNF529 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF529→partner) and Y-score (partner→ZNF529) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-b-II_pS660 →	-0.208	-1.415	.044	.046	3	2
UCEC	ATM →	-0.563	-3.308	<.001	.009	3	2
UCEC	Bax →	+0.242	+1.700	.007	.040	3	2
UCEC	Caspase-7-cleavedD198 →	+0.747	+2.242	<.001	.005	3	2
UCEC	4E-BP1 →	+0.299	+2.169	.003	.003	3	2
UCEC	C-Raf →	+0.185	+1.807	<.001	.025	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

ZNF529 survival (RNA) · tumor vs normal (RNA) · all ZNF529 data types