ZNF529-AS1

Across TCGA pan-cancer cohorts, ZNF529-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF529-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ZNF529-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF529-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.

ACC, KIRC, and LIHC are the cancer types where ZNF529-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.367	0.838	<.001	95	view →
KIRC	DFS	Median	II,III,IV	0.413	0.619	<.001	94	view →
LIHC	DFS	Tertile	All	0.419	0.645	<.001	64	view →
UCS	DFS	Tertile	III,IV	0.625	0.175	<.001	56	view →
LGG	DFS	Median	All	0.604	0.865	<.001	54	view →
SKCM	DFS	Median	II,III,IV	0.488	0.675	.007	31	view →
PRAD	DFS	Quartile	All	0.770	0.918	.002	18	view →
BLCA	OS	Quartile	II,III,IV	0.798	0.674	.019	14	view →
UVM	OS	Quartile	II,III,IV	0.819	0.392	.009	13	view →
CESC	OS	Tertile	IV	0.590	0.080	.035	12	view →
ESCA	DFS	Median	II,III,IV	0.390	0.589	.002	12	view →
THCA	DFS	Median	III,IV	0.738	0.954	.015	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF529-AS1–ACC (OS)

Open the ACC breakdown →