Across TCGA patient cohorts, ZNF527 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,025 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF527-associated proteins across cancer lineages are WIZ, XRCC1, and ARID4B. Each is linked with ZNF527 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF527-to-partner and partner-to-ZNF527 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF527→partner) and Y-score (partner→ZNF527) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WIZ →	+0.286	+0.452	.001	.005	3	6
GBM	XRCC1 →	+0.401	+0.667	<.001	<.001	3	6
HNSC	ARID4B →	+0.213	+0.550	<.001	.001	3	5
GBM	UBA2 →	+0.301	+0.546	<.001	<.001	3	5
GBM	SAE1 →	+0.350	+0.533	<.001	<.001	3	5
LUAD	HNRNPH1 →	+0.244	+0.446	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,025 associations by consensus.

Exploration

ZNF527 survival (RNA) · tumor vs normal (RNA) · all ZNF527 data types