ZNF526

Across TCGA patient cohorts, ZNF526 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,734 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZNF526-associated proteins across cancer lineages are XRCC1, PNKP, and SF3A3. Each is linked with ZNF526 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF526-to-partner and partner-to-ZNF526 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF526 versus XRCC1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF526→partner) and Y-score (partner→ZNF526) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XRCC1 →	+0.346	+0.492	<.001	<.001	3	7
GBM	PNKP →	+0.307	+0.431	<.001	<.001	3	6
GBM	SF3A3 →	+0.218	+0.297	<.001	<.001	3	6
GBM	SAE1 →	+0.283	+0.260	<.001	<.001	3	6
UCEC	POLR2E →	+0.212	+0.538	<.001	<.001	3	5
LSCC	DHX9 →	+0.203	+0.444	.007	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,734 associations by consensus.

ZNF526 vs XRCC1 — LSCC

Explore this scatter interactively →