ZNF526

Across TCGA patient cohorts, ZNF526 protein abundance is significantly associated with the RNA expression of many other genes, with 5,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF526-associated genes across cancer lineages are ACVR2B, ALOX5AP, and ZNF575. Each is linked with ZNF526 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF526-to-partner and partner-to-ZNF526 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF526 versus ACVR2B in LSCC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF526→partner) and Y-score (partner→ZNF526) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACVR2B →	+0.488	+0.228	.003	.002	2	4
GBM	ALOX5AP →	-0.905	-0.474	<.001	<.001	3	3
LSCC	ZNF575 →	+0.437	+0.242	<.001	.005	3	3
GBM	ZNF180 →	+0.508	+0.490	<.001	<.001	3	3
GBM	CRLF3 →	+0.479	+0.517	<.001	<.001	3	3
GBM	C17orf113 →	+0.700	+0.535	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,490 associations by consensus.

ZNF526 vs ACVR2B — LSCC

Explore this scatter interactively →