Across TCGA patient cohorts, ZNF525 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,028 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF525-associated proteins across cancer lineages are TRIM28, PNKP, and PAFAH1B3. Each is linked with ZNF525 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF525-to-partner and partner-to-ZNF525 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF525→partner) and Y-score (partner→ZNF525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM28 →	+0.362	+0.649	<.001	.003	3	6
BRCA	PNKP →	+0.421	+0.915	<.001	<.001	3	4
BRCA	PAFAH1B3 →	+0.413	+0.570	<.001	<.001	3	4
BRCA	IRF2BP1 →	+0.311	+0.529	.001	.004	3	4
LSCC	LIG1 →	+0.481	+0.561	.001	.004	3	4
HNSC	ZNF740 →	+0.454	+1.208	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,028 associations by consensus.

Exploration

ZNF525 survival (RNA) · tumor vs normal (RNA) · all ZNF525 data types