ZNF525

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF525 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF525-associated genes across cancer lineages are Cyclin-B1, mTOR_pS2448, and MEK1. Each is linked with ZNF525 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF525-to-partner and partner-to-ZNF525 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF525→partner) and Y-score (partner→ZNF525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCyclin-B1 →+0.609+3.321<.001<.00134
UCECmTOR_pS2448 →-0.084-1.234.041.03833
UCECMEK1 →+0.333+1.540<.001.00132
COADATM →-0.594-3.000<.001.03523
COADCaspase-7-cleavedD198 →+0.755+2.330.034.02032
UCECFoxM1 →+0.158+1.050.026.02332
Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

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