Across TCGA cell cohorts, ZNF525 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF525-associated genes across cancer lineages are ELSPBP1, KRT25, and KRTAP10-1. Each is linked with ZNF525 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF525-to-partner and partner-to-ZNF525 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF525→partner) and Y-score (partner→ZNF525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELSPBP1 →	+0.152	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KRT25 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KRTAP10-1 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ANKRD66 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	OR5V1 →	+0.010	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OPN1MW3 →	+0.004	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

ZNF525 survival (RNA) · tumor vs normal (RNA) · all ZNF525 data types