ZNF524

Across TCGA patient cohorts, ZNF524 mutation is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF524-associated genes across cancer lineages are KRTAP13-4, RPL7P55, and RNU6-420P. Each is linked with ZNF524 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF524-to-partner and partner-to-ZNF524 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP13-4 grouped by ZNF524-low versus ZNF524-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF524→partner) and Y-score (partner→ZNF524) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KRTAP13-4 →	+0.057	+6.221	<.001	.001	3	1
HNSC	RPL7P55 →	+0.061	+5.368	<.001	.005	3	1
HNSC	RNU6-420P →	+0.386	+5.368	<.001	.005	3	1
UCEC	MIR2467 →	+0.401	+3.063	.009	.004	3	1
SKCM	LINC00273 →	+0.056	+5.159	<.001	.007	3	1
SKCM	GTF3AP2 →	+0.151	+5.037	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

KRTAP13-4 by ZNF524 expression — HNSC

Explore this box plot interactively →