ZNF524

Across TCGA patient cohorts, ZNF524 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF524-associated genes across cancer lineages are CD8+ naive T-cells, Th2 cells, and mv Endothelial cells. Each is linked with ZNF524 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF524-to-partner and partner-to-ZNF524 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by ZNF524-low versus ZNF524-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF524→partner) and Y-score (partner→ZNF524) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.033	+3.042	.031	.018	3	2
UCEC	Th2 cells →	+0.213	+3.000	.041	.037	3	1
UCEC	mv Endothelial cells →	-0.030	-2.989	.028	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by ZNF524 expression — UCEC

Explore this box plot interactively →