ZNF524

Across TCGA cell cohorts, ZNF524 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,919 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF524-associated GO terms across cancer lineages are Negative regulation of NK T cell activation, Sperm motility, and Flagellated sperm motility. Each is linked with ZNF524 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF524-to-partner and partner-to-ZNF524 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of NK T cell activation grouped by ZNF524-low versus ZNF524-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF524→partner) and Y-score (partner→ZNF524) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of NK T cell activation →	+0.783	+0.849	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.103	-0.745	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.103	-0.745	<.001	<.001	3	12
OESOPHAGUS	Protein localization to condensed chromosome →	-0.149	-0.918	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.097	-0.682	<.001	<.001	3	11
BONE	Regulation of protein localization to cell periphery →	+0.085	+1.101	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,919 associations by consensus.

Negative regulation of NK T cell activation by ZNF524 expression — SOFT_TISSUE

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