Across TCGA patient cohorts, ZNF521 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,470 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF521-associated proteins across cancer lineages are ZNF521_S273, CNN3, and MSRB3. Each is linked with ZNF521 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF521-to-partner and partner-to-ZNF521 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF521→partner) and Y-score (partner→ZNF521) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF521_S273 →	+1.071	+1.868	<.001	<.001	3	10
OV	CNN3 →	+0.690	+1.213	<.001	<.001	3	9
UCEC	MSRB3 →	+0.812	+1.353	<.001	<.001	3	9
LSCC	PALLD →	+0.760	+1.142	<.001	<.001	3	8
COAD	PARVA →	+0.580	+0.688	<.001	<.001	3	8
LSCC	PDLIM4 →	+0.624	+0.952	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,470 associations by consensus.

Exploration

ZNF521 survival (RNA) · tumor vs normal (RNA) · all ZNF521 data types