Across TCGA patient cohorts, ZNF521 protein abundance is significantly associated with the RNA expression of many other genes, with 8,296 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF521-associated genes across cancer lineages are CRISPLD2, GAS1, and RASL12. Each is linked with ZNF521 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF521-to-partner and partner-to-ZNF521 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF521→partner) and Y-score (partner→ZNF521) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CRISPLD2 →	+1.052	+0.938	<.001	<.001	3	6
HNSC	GAS1 →	+1.492	+1.147	<.001	<.001	3	6
UCEC	RASL12 →	+0.948	+0.686	.001	.004	3	4
GBM	MEOX2 →	+1.773	+0.295	.001	.002	3	4
BRCA	RSPO3 →	+0.967	+0.815	<.001	<.001	3	4
LSCC	CACNA1C →	+0.826	+0.738	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,296 associations by consensus.

Exploration

ZNF521 survival (RNA) · tumor vs normal (RNA) · all ZNF521 data types