Across TCGA cell cohorts, ZNF521 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,776 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZNF521-associated GO terms across cancer lineages are Positive regulation of blood pressure by epinephrine-norepinephrine, Positive regulation of telomere maintenance, and Coenzyme A catabolic process. Each is linked with ZNF521 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF521-to-partner and partner-to-ZNF521 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF521→partner) and Y-score (partner→ZNF521) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.710	+1.504	<.001	<.001	3	7
CNS	Positive regulation of telomere maintenance →	+0.031	+1.217	.002	.001	3	7
CNS	Coenzyme A catabolic process →	-0.834	-1.557	<.001	<.001	3	6
SOFT_TISSUE	Malonyl-CoA catabolic process →	-0.839	-2.129	<.001	<.001	3	6
KIDNEY	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.070	+0.651	.004	.007	3	6
BONE	Regulation of cell-substrate junction organization →	+0.116	+1.482	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,776 associations by consensus.

Exploration

ZNF521 survival (RNA) · tumor vs normal (RNA) · all ZNF521 data types