Across TCGA cell cohorts, ZNF521 mutation is significantly associated with the mutation status of many other genes, with 4,107 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF521-associated genes across cancer lineages are ZNF865, ATP2A1, and SULF2. Each is linked with ZNF521 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF521-to-partner and partner-to-ZNF521 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF521→partner) and Y-score (partner→ZNF521) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZNF865 →	+5.000	+4.044	.008	.008	1	5
CNS	ATP2A1 →	+5.000	+4.044	.008	.008	1	5
CNS	SULF2 →	+5.000	+4.044	.008	.008	1	5
OESOPHAGUS	DYNC2H1 →	+2.830	+3.146	.006	.006	1	5
LUNG_NSCLC_LUAD	SCFD1 →	+4.491	+3.117	.004	.004	1	5
LARGE_INTESTINE	ANKRD17 →	+2.050	+2.222	.001	.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,107 associations by consensus.

Exploration

ZNF521 survival (RNA) · tumor vs normal (RNA) · all ZNF521 data types